Orexin B (Hypocretin-2)

Orexin B (Hypocretin-2): Ultra-Pure Research Peptide – Verified Purity & Trusted Results

🔬 High-Purity Research Peptide – ≥99% Verified Peptide-Grade, Precision Formulated for Laboratory Research
📜 Scientifically Validated – Certificate of Analysis (COA) & HPLC Tested for Absolute Quality Assurance
🌍 Globally Trusted by Leading Scientific Laboratories & Research Institutions

Chemical Information:

• Compound Name: Orexin B (Hypocretin-2)
• Synonyms: Orexin B, Hypocretin-2, Human Orexin B (TFA Salt)
• CAS Number: 205640-91-1
• Molecular Formula: C₁₂₃H₂₁₂N₄₄O₃₅S
• Molecular Weight: 2937.3 g/mol (PubChem Reference)
• Purity: ≥99% (Peptide-Grade, confirmed via HPLC)

Scientific Overview:

Orexin B, also known as Hypocretin-2, is a neuropeptide synthesised primarily in the lateral hypothalamus, implicated extensively in the regulation of sleep-wake cycles, neuroendocrine control, and energy metabolism. It binds selectively to orexin receptor 2 (OX₂R) and has been widely studied for its roles in sleep-wake regulation, stress response modulation, cognitive functions, and homeostatic processes. Researchers frequently utilise Orexin B in investigations exploring the underlying neurobiology of sleep disorders, metabolic balance, and neurological functioning.

Key Scientific References & Literature:

• Wikipedia – Orexin (Hypocretin): Comprehensive overview of Orexin peptides, including their neurobiological functions, receptors, and physiological roles.
• Sakurai, T. et al. (1998) – "Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior," Cell:
  Seminal research detailing the discovery and functions of Orexin peptides and their role in feeding and neuroendocrine regulation.
• Scammell, T.E. et al. (2017) – "Orexin Receptor Antagonists: Neurobiology, Clinical Use, and Potential for the Treatment of Neuropsychiatric Disorders," Frontiers in Neuroscience:
  An in-depth review of Orexin receptor pathways, their neurophysiological roles, and therapeutic implications for research applications.

Why Choose Our Orexin B (Hypocretin-2)?

✅ Precision HPLC Analysis – Ensuring consistent ≥99% purity for accurate and reliable experimental outcomes
✅ Certificate of Analysis (COA) – Instantly accessible via QR Code for maximum transparency and convenience
✅ Material Safety Data Sheet (MSDS) – Detailed safety documentation provided for safe laboratory handling and compliance
✅ Manufactured in the UK – Synthesised under stringent laboratory quality controls, free from contaminants
✅ Secure & Rapid Delivery – Ensuring swift dispatch, secure packaging, and peptide stability during transit
✅ Third-Party Verification – Independent testing available upon request to confirm purity and quality

For Research Use Only

Our Orexin B (Hypocretin-2) is strictly produced for scientific research and laboratory experimentation only. It is explicitly not intended for human consumption or therapeutic application.

Advance your neuroscience and metabolic research confidently with our ultra-pure Orexin B (Hypocretin-2), meticulously synthesised for optimal reproducibility and scientifically rigorous outcomes.